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, R. Ward Dermatology Department Kingston Hospital Galsworthy Road Kingston upon Thames UK Search for other works by this author on: Oxford Academic N. Fox Dermatology Department Kingston Hospital Galsworthy Road Kingston upon Thames UK Search for other works by this author on: Oxford Academic J. Natkunarajah Dermatology Department Kingston Hospital Galsworthy Road Kingston upon Thames UK Search for other works by this author on: Oxford Academic
Clinical and Experimental Dermatology, Volume 46, Issue 5, 1 July 2021, Pages 956–957, https://doi.org/10.1111/ced.14628
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01 July 2021
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R. Ward, N. Fox, J. Natkunarajah, Scurvy: a forgotten cause of purpuric rash, Clinical and Experimental Dermatology, Volume 46, Issue 5, 1 July 2021, Pages 956–957, https://doi.org/10.1111/ced.14628
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Conflict of interest: the authors declare that they have no conflicts of interest.
A 49‐year‐old man presented to hospital with hypotension following a collapse. He had been generally unwell with shortness of breath and had developed bruising over his abdomen, arms and legs. His medical history included schizophrenia, Type 2 diabetes and hypertension. He lived alone, did not consume alcohol and his diet consisted of mainly pre‐packed sandwiches. He denied misuse of any illicit substances or medications.
On physical examination the patient was alert and orientated, and vital signs were unremarkable apart from hypotension (blood pressure 60/30 mmHg; pulse 78 beats/min). There was a widespread nonblanching petechial exanthem over the legs, arms and torso (Fig. 1a), with a significant palpable purpuric plaque on the left lateral lower leg. Initial differential diagnoses included sepsis, acute viral infection, small vessel vasculitis, idiopathic thrombocytopenic purpura, disseminated intravascular coagulation or haematological malignancy.
Blood results showed mild acute kidney injury, slightly raised inflammatory markers and microcytic anaemia [haemoglobin 109 g/L (normal range 130–180 g/L), mean corpuscular volume 75.9 fL (80–96 fL)]. International normalized ratio and platelet and fibrinogen levels were normal. Twelve‐lead electrocardiography showed normal sinus rhythm and chest radiography was clear. Urinalysis revealed microscopic haematuria and proteinuria.
Issue Section:
Correspondence > Viewpoints in dermatology
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