Endovascular thrombectomy beyond 24 hours from last known well: a systematic review with meta-analysis (2024)

1. http://orcid.org/0000-0002-8413-6954Aaron Rodriguez-Calienes1,2,
2. http://orcid.org/0000-0002-8107-9632Milagros Galecio-Castillo1,
3. http://orcid.org/0000-0001-5326-1907Juan Vivanco-Suarez1,
4. Ghada A Mohamed3,
5. http://orcid.org/0000-0002-3646-3635Gabor Toth4,
6. http://orcid.org/0000-0001-5726-4478Amrou Sarraj5,
7. Deep Pujara5,
8. http://orcid.org/0000-0002-7788-8074AJ A Chowdhury1,
9. http://orcid.org/0000-0003-3697-5697Mudassir Farooqui1,
10. Malik Ghannam1,
11. http://orcid.org/0000-0003-2764-2268Edgar A Samaniego6,
12. Tudor G Jovin7,
13. http://orcid.org/0000-0002-3408-1297Santiago Ortega-Gutierrez6

1. ¹Department of Neurology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
2. ²Neuroscience, Clinical Effectiveness and Public Health Research Group, Universidad Científica del Sur, Lima, Peru
3. ³Department of Neurology, Medical University of South Carolina, Charleston, South Carolina, USA
4. ⁴Cerebrovascular Center, Cleveland Clinic, Cleveland, Ohio, USA
5. ⁵Department of Neurology, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA
6. ⁶Department of Neurology, Neurosurgery & Radiology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
7. ⁷Cooper Neurological Institute, Cooper University Hospital, Camden, New Jersey, USA

1. Correspondence to Dr Santiago Ortega-Gutierrez, Neurology, Neurosurgery and Radiology, University of Iowa Hospitals & Clinics, Iowa City, IA 52242, USA; santy-ortega{at}uiowa.edu

• Thrombectomy
• Stroke
• Intervention

• Thrombectomy
• Stroke
• Intervention

Footnotes

• X @AaronCalienes, @mili_galecio, @jsvivanco1, @GaborTothMD, @amrsarrajMD, @FunkyMegacolon, @esamaniego, @CerebrovascLab

• Contributors All authors contributed to the study design and drafting of the manuscript. The search was completed by ARC, JVS, and MGC; screening of articles by ARC, JVS, and MGC; data extraction by ARC, JVS, MGC, and AAC; quality control by ARC, JVS, and AAC; statistical analysis by MGC and ARC; data interpretation by ARC, JVS, MF, and SOG; critical revision by GAM, GT, AS, DP, MF, MG, EAS, TGJ, and SOG. SOG is responsible for the overall content as guarantor.

• Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

• Competing interests SOG: grants from NIH, Stryker, Medtronic, Microvention, MEthinks, IschemiaView, Viz.ai, Siemens; consulting fees from Medtronic and Stryker. TGJ: advisor and investor for Anaconda, Route92, Viz.AI, FreeOx, Blockade Medical, and Methinks; grant support from Medtronic and from Stryker Neurovascular in his capacity as principal investigator for DAWN and AURORA; he received personal fees in his role on the Data Safety Monitoring Board. GT: consultant: Dynamed and Micronvention. AS: principal investigator of the SELECT (Optimizing Patient’s Selection for Endovascular Treatment in Acute Ischemic Stroke) and SELECT-2 trials through a grant from Stryker Neurovascular to the University of Texas McGovern–Houston; consultant: Stryker; speaker bureau member: Stryker.

• Provenance and peer review Not commissioned; externally peer reviewed.

• Supplemental material This content has been supplied by the author(s). It has not been vetted by BMJ Publishing Group Limited (BMJ) and may not have been peer-reviewed. Any opinions or recommendations discussed are solely those of the author(s) and are not endorsed by BMJ. BMJ disclaims all liability and responsibility arising from any reliance placed on the content. Where the content includes any translated material, BMJ does not warrant the accuracy and reliability of the translations (including but not limited to local regulations, clinical guidelines, terminology, drug names and drug dosages), and is not responsible for any error and/or omissions arising from translation and adaptation or otherwise.