[PDF] Value of Sonazoid-enhanced ultrasonography in characterizing indeterminate focal liver lesions on gadoxetic acid-enhanced liver MRI in patients without risk factors for hepatocellular carcinoma | Semantic Scholar (2024)

[PDF] Semantic Reader

The Kupffer phase best shows hypoenhancing changes in LR-5 lesions and is expected to improve the sensitivity for HCC in high-risk patients.

The combined interpretation of gadoxetate-enhanced MRI and second-line CEUS using Sonazoid, focusing on TP hypointensity, restricted diffusion, and KPD, may be optimal for further characterizing LR-3 and LR-4 observations.

Gadoxetic acid disodium-enhancedMRI is of clinical benefit relative to unenhanced MRI and spiral CT for a radiological diagnosis of liver lesions.

G gadoxetic acid-enhanced MRI showed higher diagnostic accuracy and sensitivity than did MDCT for the detection of hepatic metastases and for the differentiation between hepatic Metastases and hepatic haemangiomas or cysts.

It is concluded that CEUS and SCT provide a similar diagnostic accuracy in the characterization of FLL, with a good degree of correlation between the two techniques.

The combined assessment of hepatocellular nodule vascularity at CT and CEUS improved sensitivity in the diagnosis of malignancy in patients with liver cirrhosis.

Results showed a similar efficacy for Sonazoid™ and SonoVue® in diagnosing FLLs as benign or malignant, and underlined the benefit of CEUS imaging over unenhanced ultrasound imaging in reaching a confident diagnosis without having to refer patients for additional imaging exams.

Comparison-enhanced 3D US potentially can be used to characterize focal liver tumors and there were no significant differences between the two modalities.

The state-of-the-art MRI liver protocol is reviewed, briefly discussing different sequence types, the unique characteristics of imaging non-cooperative patients and the role of hepatocyte-specific contrast agents are discussed.

CEUS is an accurate tool to stratify the risk of malignancy in FLLs and the second-generation CAs, especially Sonazoid, may greatly improve diagnostic performance.

...

...